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Study Shows Neuroblastoma Evolves Rapidly, Limiting Treatment Targets
A recent genomic study of neuroblastoma reinforces the challenges of treating the most aggressive forms of this disease. Contrary to expectations, the researchers found relatively few recurrent gene...
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CBS Sunday Morning Features ALK Cancer Trial at Children’s Hospital
Yesterday, CBS Sunday Morning featured a story on the anaplastic lymphoma kinase, or ALK, clinical trial for lymphoma and neuroblastoma and CHOP’s partnership with the Alex’s Lemonade Stand Foundation,...
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CHOP Cancer Expert Garrett Brodeur Honored with Pediatric Oncology Award and...
Dr. Brodeur has focused on identifying the genes, proteins and biological pathways that give rise to neuroblastoma and drive its clinical behavior. A pediatric oncologist with the Cancer Center at The...
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CHOP Cancer Experts Awarded Alex’s Lemonade Stand Grants
As part of its mission to find “a cure for all children with cancer,” Alex’s Lemonade Stand Foundation recently announced more than $7 million in new grants to researchers around the country, including...
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St. Baldrick’s Foundation Awards Children’s Hospital More than $650,000
Monrovia, Calif.-based St. Baldrick’s Foundation recently announced $699,186 in grants to one consortium and three cancer researchers at The Children’s Hospital of Philadelphia. The Testicular...
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Proton Therapy Offers New, Precise Cancer Treatment for Children with...
Protons are the positively charged particles in an atom’s nucleus, and are used in therapy to destroy DNA in tumors and prevent cancer cells from multiplying. Proton therapy, which uses high-energy...
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Oncologist Honored for Neuroblastoma Research
The Advances in Neuroblastoma Research Association (ANRA) recently presented its highest honor to pediatric oncologist Garrett M. Brodeur, MD, of the Cancer Center at The Children’s Hospital of...
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Scholar Hope Grant Supports Neuroblastoma Research
©2014 Paul Crane, Crane Photography, Inc. Pediatric oncology researchers at The Children’s Hospital of Philadelphia are driven to find new treatments for childhood cancer, and the Hyundai Hope On...
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Neuroblastoma Studies Show Promise of Nanoparticles in Fighting Tumors
The nanoparticle is coated with a polymer layer masking it from recognition and elimination by the immune system as it circulates through the body. On reaching a tumor, it slowly releases a drug...
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Researchers Pinpoint Mutations in Relapsed Neuroblastoma
An international collaboration of researchers has identified several progressive series of mutations that occur in tumor cells responsible for aggressive subsets of neuroblastoma that relapse after...
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New Research Consortium Aims to Identify Drugs for Pediatric Cancers
The Children’s Hospital of Philadelphia and four other high-profile oncology research programs plus a coordinating center joined the new Pediatric Preclinical Testing Consortium (PPTC) launched by the...
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Young Investigator Seeks a Target for Targeted Neuroblastoma Therapy
It is scary to learn your child has neuroblastoma, a tumor of the peripheral nervous system that is the most common cancer in infants. It is scarier still when you get test results that show your child...
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Dancing Eyes Brought a Research Team Together
It started at the end of a long day. Jessica Panzer, MD, PhD, then just a few weeks into her pediatric neurology residency at The Children’s Hospital of Philadelphia, was about to go home. Instead,...
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Study Gives New Insights Into Genetic Predisposition to Neuroblastoma
Pediatric oncology researchers have narrowed down a culprit in an aggressive form of the childhood cancer neuroblastoma that makes the disease progress once tumors form. By mapping how DNA interacts...
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Looking Back on the Year of Precision Medicine
In 2016, one million or more volunteers may begin enrolling in one of the largest long-term medical research studies ever planned. It aims to inform future therapies targeted to the molecular,...
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Scientists Discover a Better ALK Inhibitor to Treat Neuroblastoma
Pediatric cancer researchers at The Children’s Hospital of Philadelphia believe they have succeeded in their search for a powerful next-generation drug for neuroblastoma tumors with mutations in the...
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CHOP Research In the News: Teen Crime, Tech Innovators, Tackling Concussions
Our news highlights from this week cover some provocative topics in pediatric research, from serious teen violence in Philadelphia neighborhoods to head trauma injuries in student athletes across the...
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CHOP Research In the News: Clinical Research in the Spotlight
We like to highlight the whole range of research at The Children’s Hospital of Philadelphia, from basic discoveries at the lab bench to clinical findings applied at the patient’s bedside. But we have...
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New Neuroblastoma Research Scholars Program Supports Young Scientist
Young scientists may have passion and brilliant ideas, but unfortunately, they often do not add up to federal funding dollars. This is particularly problematic in pediatric cancer research, which...
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CHOP Research In the News: Cancer Moonshot, Why Children Get Cancer, and a...
Welcome back to our weekly roundup of pediatric research news from The Children’s Hospital of Philadelphia. This week, as many students head back to school, the American Academy of Pediatrics (AAP) is...
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